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Vittek J. Department of Medicine, New York
Medical College, Valhalla 10595, USA.
The primary objective of this review was to assess the size and
consistency of Royal Jelly (RJ)
effect on serum lipids in experimental animals and humans. The
data from animal studies were pooled, where possible, and statistically
evaluated by Student's t-test. Meta-analysis was used for
the evaluation of human trials. It was found that
royal jelly significantly decreased serum and liver total
lipids and cholesterol levels in rats and rabbits and also retarded
the formation of atheromas in the aorta of rabbits fed a hyperlipemic
diet. Meta-analysis of the controlled human trials of royal jelly
to reduce hyperlipidemia showed a significant reduction in total
serum lipids and cholesterol levels and normalization of HDL and
LDL as determined from decrease in beta/alpha lipoproteins. The
best available evidence suggests that royal jelly at approximately
50 to 100 mg per day, decreased total serum cholesterol levels
by about 14%, and total serum lipids by about 10% in the group
of patients studied. |
